Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Tubulin polymerization-IN-25

Tubulin polymerization-IN-25 (compound 17f) is a dual inhibitor of tubulin polymerization and farnesyl transferase (FTase) with IC50s of 1.11 μM and 0.39 μM, respectively. Tubulin polymerization-IN-25 displays cytotoxicity and excellent antitumor activity [1].

Product Specifications

CAS Number

2490538-46-8

UNSPSC

12352005

Target

Farnesyl Transferase; Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tubulin-polymerization-in-25.html

Solubility

10 mM in DMSO

Smiles

CC(C1=CC(C(C2=CC=C3NC4=C(C=CC=C4)SC3=C2)=O)=C5C=C(OC)C=CN15)=O

Molecular Formula

C24H18N2O3S

Molecular Weight

414.48

References & Citations

[1]Iuliana-Monica Moise, et al. Indolizine-phenothiazine hybrids as the first dual inhibitors of tubulin polymerization and farnesyltransferase with synergistic antitumor activity. Bioorg Chem. 2020 Oct; 103: 104184.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Human PLUNC ELISA Kit
orb441662-01 48 Tests

Human PLUNC ELISA Kit

Sign In for Pricing
View Details
Human PLUNC ELISA Kit
orb441662-02 96 Tests

Human PLUNC ELISA Kit

Sign In for Pricing
View Details
Recombinant Schizosaccharomyces Pombe SPAC8C9.12c Protein (aa 1-303)
VAng-Yyj5828-inquire Inquire

Recombinant Schizosaccharomyces Pombe SPAC8C9.12c Protein (aa 1-303)

Sign In for Pricing
View Details
OASG07214-100UL - Tlr13 Antibody
OASG07214-100UL 100 µL

OASG07214-100UL - Tlr13 Antibody

Sign In for Pricing
View Details
Canine Tumor Protein, Translationally Controlled 1 ELISA Kit
MBS071271-01 48 Well

Canine Tumor Protein, Translationally Controlled 1 ELISA Kit

Sign In for Pricing
View Details
Canine Tumor Protein, Translationally Controlled 1 ELISA Kit
MBS071271-02 96 Well

Canine Tumor Protein, Translationally Controlled 1 ELISA Kit

Sign In for Pricing
View Details