Polyinosinic acid

Polyinosinic acid is a single stranded homonucleic acid, which is a Toll-like Receptor 3 (TLR3) ligand. Polyinosinic acid enhances cellular immune response through TLR3 and TRIF. Polyinosinic acid has potential applications in immune regulation[1].

Product Specifications

CAS Number

[30918-54-8]

UNSPSC

12352005

Target

Toll-like Receptor (TLR)

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/polyinosinic-acid.html

Solubility

10 mM in DMSO

Smiles

O=P(O)(O)OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C3=C(C(N=CN3)=O)N=C2)O1.[x]

Molecular Formula

(C10H13N4O8P) x

References & Citations

[1]Marshall-Clarke S, et al. Polyinosinic acid is a ligand for toll-like receptor 3. J Biol Chem. 2007 Aug 24;282 (34) :24759-66.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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