ZW290
ZW290 is a compound to activate brown adipose tissue (BAT) thermogenic function. ZW290 increases the expression of uncoupling Protein 1 (UCP1) protein and inhibits ATP synthesis in BAT[1].
Product Specifications
CAS Number
[2411852-67-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
ATP Synthase
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/zw290.html
Purity
99.60
Solubility
10 mM in DMSO
Smiles
O=C1N(C2=CC=C(C=C2)OC)C(N/C1=C\C3=CC(OC)=C(C=C3)OCC(O)=O)=S
Molecular Formula
C20H18N2O6S
Molecular Weight
414.43
Precautions
H302, H315, H319
References & Citations
[1]Nan Wang, et al. ZW290 Increases Cold Tolerance by Inducing Thermogenesis via the Upregulation of Uncoupling Protein 1 in Brown Adipose Tissue In Vitro and In Vivo. Lipids. 2019 May;54 (5) :265-276.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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