Fosdevirine
Fosdevirine (GSK2248761) is is a potent, selective, non-nucleoside reverse transcriptase inhibitor (NNRTI) of human immunodeficiency virus type 1 (HIV-1) replication with low nanomolar activity in vitro. Fosdevirine shows good activity against a broad range of HIV-1 strains, including efavirenz -resistant clinical isolates[1].
Product Specifications
CAS Number
1018450-26-4
Product Name Alternative
GSK2248761; FDV
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
HIV; Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/fosdevirine.html
Purity
98.96
Solubility
10 mM in DMSO
Smiles
CO[P@@](C1=C(C(N)=O)NC2=CC=C(Cl)C=C12)(C3=CC(/C=C/C#N)=CC(C)=C3)=O
Molecular Formula
C20H17ClN3O3P
Molecular Weight
413.79
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
HIV-1
Available Sizes
Frequently Asked Questions
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