Isopropyl dodec-11-enylfluorophosphonate
Isopropyl dodec-11-enylfluorophosphonate (IDEFP) is an organophosphorus ester that antagonizes the central cannabinoid receptor (CB1) and inhibits FAAH with similar potencies (IC50 = 2 nM) [1].
Product Specifications
CAS Number
[623114-64-7]
Product Name Alternative
IDEFP
UNSPSC
12352211
Hazard Statement
H225, H319, H336
Target
Cannabinoid Receptor; FAAH
Type
Reference compound
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/isopropyl-dodec-11-enylfluorophosphonate.html
Solubility
10 mM in DMSO
Smiles
O=P(OC(C)C)(CCCCCCCCCCC=C)F
Molecular Formula
C15H30FO2P
Molecular Weight
292.37
Precautions
H225, H319, H336
References & Citations
[1]Michael A Casasanta, et al. A chemical and biological toolbox for Type Vd secretion: Characterization of the phospholipase A1 autotransporter FplA from Fusobacterium nucleatum. J Biol Chem. 2017 Dec 8;292 (49) :20240-20254.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CB1
Curated Selection
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