Eliglustat-d4
Eliglustat-d4 is the deuterium labeled Eliglustat. Eliglustat is an specific, potent and orally active glucocerebroside synthase inhibitor with an IC50 of 24 nM[1][2].
Product Specifications
Product Name Alternative
Genz 99067-d4
UNSPSC
12352005
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Metabolic Disease
Purity
98.02
Solubility
10 mM in DMSO
Smiles
O[C@H](C1=CC2=C(C=C1)OC([2H])([2H])C([2H])([2H])O2)[C@@H](CN3CCCC3)NC(CCCCCCC)=O
Molecular Formula
C23H32D4N2O4
Molecular Weight
408.57
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]McEachern KA, et al. A specific and potent inhibitor of glucosylceramide synthase for substrate inhibition therapy ofGaucher disease. Mol Genet Metab. 2007 Jul;91 (3) :259-68.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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