Pomalidomide-piperazine
Pomalidomide-piperazine is an active compound that can be used to synthesis the E3 ligand for PROTAC[1].
Product Specifications
CAS Number
[2154342-57-9]
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pomalidomide-piperazine.html
Solubility
10 mM in DMSO
Smiles
O=C1NC(C(CC1)N2C(C3=CC=CC(N4CCNCC4)=C3C2=O)=O)=O
Molecular Formula
C17H18N4O4
Molecular Weight
342.35
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Li H, et al. Design, synthesis, and biological characterization of a potent STAT3 degrader for the treatment of gastric cancer. Front Pharmacol. 2022 Aug 12;13:944455.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
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