Ritivixibat
Ritivixibat is an inhibitor of ileal bile acid transporter (IBAT), as well as a bile acid modulator. Ritivixibat can be used for research of cardiovascular diseases, fatty acid metabolism and glucose utilization disorders, gastrointestinal diseases and liver diseases[1][2].
Product Specifications
CAS Number
2460667-52-9
UNSPSC
12352005
Target
Apical Sodium-Dependent Bile Acid Transporter
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ritivixibat.html
Solubility
10 mM in DMSO
Smiles
O=C(CCOC1=C(SC)C=C(N(CC(CCCC)(CCCC)NS2(=O)=O)C3=CC=CC=C3)C2=C1)O
Molecular Formula
C26H36N2O5S2
Molecular Weight
520.70
References & Citations
[1]Gillberg Per-Goeran, et al. Preparation of benzothiazepines as liver bile acid transport inhibitors for the treatment of liver, gastrointestinal and other disorders: United States, US20200247769. 2020-08-06.|[2]WHO Drug Information-World Health Organization (WHO) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Frequently Asked Questions
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