FGFR3-IN-4
FGFR3-IN-4 is a selective FGFR3 inhibitor, with an IC50 value of less than 50 nM. FGFR3-IN-4 is at least 10 fold more selective for FGFR3 than for FGFR1[1].
Product Specifications
CAS Number
2833706-13-9
UNSPSC
12352005
Target
FGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fgfr3-in-4.html
Solubility
10 mM in DMSO
Smiles
C[C@H](C1=C(C=CC=C1)C#N)OC2=CC(C3=C(N(C4CCN(CC4)C#N)N=C3)C)=CN5C2=C(Cl)C=N5
Molecular Formula
C26H24ClN7O
Molecular Weight
485.97
References & Citations
[1]Abraham, et al. Preparation of substituted pyrazolo[1,5-a]pyridine-3-carbonitriles and imidazo[1,2-a]pyridine-3-carbonitriles as FGFR3 inhibitors. WO2022187443.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Myosin (MYL4) Mouse Monoclonal Antibody [Clone ID: OTI2F6]](https://cdn.genprice.uk/products/937/68dd18b9061270361e908103/imageurl/cf807581.webp)
CF807581 100 µg
Myosin (MYL4) Mouse Monoclonal Antibody [Clone ID: OTI2F6]
Sign In for Pricing
View Details 
