AB-506
AB-506 is an orally active inhibitor of HBV replication targeting the viral core protein. AB-506 can bind to HBV core protein, accelerate capsid assembly and inhibit HBV pgRNA encapsidation. AB-506 can be used in chronic hepatitis B (CHB) research[1].
Product Specifications
CAS Number
2245020-50-0
UNSPSC
12352005
Target
HBV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ab-506.html
Solubility
10 mM in DMSO
Smiles
ClC(C=C1NC(C2=C3C([C@H](CC3)NC(OCC4=NN(C)C=N4)=O)=C(C=C2)F)=O)=C(C=C1)F
Molecular Formula
C21H18ClF2N5O3
Molecular Weight
461.85
References & Citations
[1]Nagraj Mani, et al. Preclinical characterization of AB-506, an inhibitor of HBV replication targeting the viral core protein. Antiviral Res. 2022 Jan;197:105211.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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