JG-258
JG-258 is an inactive negative control for Hsp70 inhibitors[1].
Product Specifications
CAS Number
2241517-83-7
UNSPSC
12352005
Target
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/jg-258.html
Solubility
10 mM in DMSO
Smiles
O=C1/C(S/C(N1CC)=C\C2=[N+](C=CS2)CC3=CC=CC=C3)=C4N(CCS/4)C.[Cl-]
Molecular Formula
C20H22ClN3OS3
Molecular Weight
452.06
References & Citations
[1]Hao Shao, et al. Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein-Protein Interactions with Heat Shock Protein 70 (Hsp70) . J Med Chem. 2018 Jul 26;61 (14) :6163-6177.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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