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NSC363998 (free base)

NSC363998 (free base) is an orally active compound. NSC363998 (free base) can suppress rCGG90 induced neurotoxicity. NSC363998 (free base) can be used for the research of neurodegenerative disorder such as Fragile X associated tremor/ataxia syndrome (FXTAS) [1].

Product Specifications

CAS Number

159357-82-1

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/nsc363998-free-base.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=C(C(C3=C1C(NCCCNCCO)=CC=C3)=O)C(NCCCNCCO)=CC=C2

Molecular Formula

C24H32N4O4

Molecular Weight

440.54

References & Citations

[1]Yunting Lin, et al. Neddylation activity modulates the neurodegeneration associated with fragile X associated tremor/ataxia syndrome (FXTAS) through regulating Sima. Neurobiol Dis. 2020 Sep;143:105013.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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