AMPK activator 10
Product Specifications
UNSPSC Description
AMPK activator 10 is an orally active, potent AMPK activator with EC150 of 44.3 nM by cell-ELISA. AMPK activator 10 increases the phosphorylation levels of ACC. AMPK activator 10 exhibits a glucose lowering effect[1].
Target Antigen
AMPK
Type
Reference compound
Related Pathways
Epigenetics;PI3K/Akt/mTOR
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ampk-activator-10.html
Solubility
10 mM in DMSO
Smiles
COCCOC1=CC(F)=C(C(CC2)=C1)[C@H]2NC3=C(Cl)C=C(NC(O[C@H]4[C@]5([H])[C@]([C@@H](CO5)O)([H])OC4)=N6)C6=N3
Molecular Weight
520.94
References & Citations
[1]Yuusuke Tamura, et al. Identification of novel benzimidazole derivatives as highly potent AMPK activators with anti-diabetic profiles. Bioorg Med Chem Lett. 2023 Jan 1;79:129059.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148684/AMPK-activator-10-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148684/
Clinical Information
No Development Reported
CAS Number
1914176-03-6
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