Pomalidomide-PEG5-C2-NH2 (hydrochloride)
Pomalidomide-PEG5-C2-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.Pomalidomide-PEG5-C2-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC[1].
Product Specifications
CAS Number
[2357117-23-6]
UNSPSC
12352005
Hazard Statement
H361
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pomalidomide-peg5-c2-nh2-hydrochloride.html
Purity
98.94
Solubility
10 mM in DMSO
Smiles
O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCOCCOCCOCCOCCOCCN)=CC=C3)=O)=O.Cl
Molecular Formula
C25H37ClN4O9
Molecular Weight
573.04
Precautions
H361
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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