Pomalidomide-PEG5-C2-NH2 (hydrochloride)

Pomalidomide-PEG5-C2-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.Pomalidomide-PEG5-C2-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC[1].

Product Specifications

CAS Number

[2357117-23-6]

UNSPSC

12352005

Hazard Statement

H361

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pomalidomide-peg5-c2-nh2-hydrochloride.html

Purity

98.94

Solubility

10 mM in DMSO

Smiles

O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCOCCOCCOCCOCCOCCN)=CC=C3)=O)=O.Cl

Molecular Formula

C25H37ClN4O9

Molecular Weight

573.04

Precautions

H361

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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