Mipomersen

Mipomersen (ISIS 301012 free base) is an antisense oligonucleotide inhibitor of apolipoprotein B (apoB) . Mipomersen has anti-HCV effect and reduces the infectivity of the HCV. Mipomersen can be used for the research of homozygous familial hypercholesterolemia (HoFH) [1][2].

Product Specifications

CAS Number

[1000120-98-8]

Product Name Alternative

ISIS 301012 (free base)

UNSPSC

12352208

Target

Apolipoprotein; HCV

Type

Oligonucleotides

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/mipomersen.html

Purity

96.88

Solubility

H2O : ≥ 100 mg/mL

Smiles

[Mipomersen]

Molecular Formula

C230H324N67O122P19S19

Molecular Weight

7179.15

References & Citations

[1]Merki E, et al. Antisense oligonucleotide directed to human apolipoprotein B-100 reduces lipoprotein (a) levels and oxidized phospholipids on human apolipoprotein B-100 particles in lipoprotein (a) transgenic mice. Circulation. 2008 Aug 12;118 (7) :743-53.|[2]Schaefer EA, et al. Apolipoprotein B100 is required for hepatitis C infectivity and Mipomersen inhibits hepatitis C. World J Gastroenterol. 2016 Dec 7;22 (45) :9954-9965.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Oligonucleotides

Clinical Information

Launched

Isoform

ApoB

Citation 01

Poult Sci. 2025 Nov 19;105 (1) :106137.|Poult Sci. 2025 Mar 6;104 (5) :104993.

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS7098776 Inquire

Recombinant Arabidopsis thaliana Protein PLANT CADMIUM RESISTANCE 6 (PCR6) , partial

Ask

View Details

MBS7173250 Inquire

Rabbit anti-Escherichia coli O81 (strain ED1a) PDXA Polyclonal Antibody

Ask

View Details

MR207124L3 10 µg

Krt25 (NM_133730) Mouse Tagged Lenti ORF Clone

Ask

View Details

TRC-A320145-1G 1 g

2-Amino-3-bromo-4-fluorophenol

Ask

View Details