STING modulator-4
STING modulator-4 (compound AIH05) is a competitive STING modulator with a Ki of 0.0933 μM for R232H STING. STING modulator-4 has an EC50 of >10 μM for p-IRF3 in THP-1 cell[1].
Product Specifications
CAS Number
2839639-72-2
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sting-modulator-4.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC2=C(C=NN2C)C(C3=NC(C4=CC=NN4CC)=CN3C)=N1)N
Molecular Formula
C17H18N8O
Molecular Weight
350.38
References & Citations
[1]Ketan Satish GAJIWALA, et al. Modulators of sting (stimulator of interferon genes) . WO2022195462A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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