LDH-IN-2
LDH-IN-2, a salicylic acid derivative, is an inhibitor of glycolate oxidase (GO) . LDH-IN-2 decreases oxalate output in hyperoxaluric hepatocytes. LDH-IN-2 can be used for research of primary hyperoxaluria type 1 (PH1) [1].
Product Specifications
CAS Number
893739-96-3
UNSPSC
12352005
Target
Glycolate Oxidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ldh-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(O)C=CC(C2=CC=CO2)=C1)O
Molecular Formula
C11H8O4
Molecular Weight
204.18
References & Citations
[1]Moya-Garzón MD, et al. Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1. J Med Chem. 2018 Aug 23;61 (16) :7144-7167.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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