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1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol

1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol is an anionic phospholipid, can be used for drug delivery and the synthesis of liposomes.

Product Specifications

CAS Number

217939-97-4

Product Name Alternative

DSPG

UNSPSC

12352200

Target

Liposome

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dspg.html

Solubility

10 mM in DMSO

Smiles

OCC(O)COP(OC[C@@H](COC(CCCCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCCCC)=O)(O)=O

Molecular Formula

C42H83O10P

Molecular Weight

779.08

References & Citations

[1]Benne N, van Duijn J, Lozano Vigario F, et al. Anionic 1,2-distearoyl-sn-glycero-3-phosphoglycerol (DSPG) liposomes induce antigen-specific regulatory T cells and prevent atherosclerosis in mice. J Control Release. 2018;291:135-146.|[2]Maruyama T, Sugii M, Omata D, et al. Effect of lipid shell composition in DSPG-based microbubbles on blood flow imaging with ultrasonography. Int J Pharm. 2020;590:119886. |[3]Momtazi-Borojeni AA, Abdollahi E, Jaafari MR, Banach M, Watts GF, Sahebkar A. Negatively-charged Liposome Nanoparticles Can Prevent Dyslipidemia and Atherosclerosis Progression in the Rabbit Model. Curr Vasc Pharmacol. 2022;20 (1) :69-76.

Shipping Conditions

Room temperature

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Frequently Asked Questions

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