Q-FTAA
Q-FTAA binds to Aβ1-42 fibrils with EC50 values of 330-630, 300-500 nM for Aβ1-42 fibrils, alzheimer's disease PIB binding complex (ADPBC), respectively. q-FTAA has the potential for the research of Alzheimer's disease (AD) [1].
Product Specifications
CAS Number
[1352477-22-5]
UNSPSC
12352005
Target
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/q-ftaa.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(C2=CC(CC(O)=O)=C(C3=CC=C(C4=C(CC(O)=O)C=CS4)S3)S2)S1)O
Molecular Formula
C21H14O6S4
Molecular Weight
490.59
References & Citations
[1]Bäck M, et al. Anionic Oligothiophenes Compete for Binding of X-34 but not PIB to Recombinant Aβ Amyloid Fibrils and Alzheimer's Disease Brain-Derived Aβ. Chemistry. 2016 Dec 19;22 (51) :18335-18338.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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