Calpain Inhibitor XI
Calpain Inhibitor XI is a reversible covalent inhibitor of calpain-1. Calpain Inhibitor XI can be used for the research of neurodegenerative disorders[1].
Product Specifications
CAS Number
145731-49-3
UNSPSC
12352005
Target
Proteasome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/calpain-inhibitor-xi.html
Solubility
10 mM in DMSO
Smiles
O=C(NC(CC(C)C)C(NC(CC)C(C(NCCCN1CCOCC1)=O)=O)=O)OCC2=CC=CC=C2
Molecular Formula
C26H40N4O6
Molecular Weight
504.62
References & Citations
[1]Rachel C Knopp, et al. Extending the Calpain-Cathepsin Hypothesis to the Neurovasculature: Protection of Brain Endothelial Cells and Mice from Neurotrauma. ACS Pharmacol Transl Sci. 2021 Feb 2;4 (1) :372-385.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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