β2AR/M3-receptor agonist-1
β2AR/M3-receptor agonist-1 (example 9) is a potent β2AR and M3 receptor agonist. β2AR/M3-receptor agonist-1 shows M3 receptor affinity with a pIC50 value of 9.3. β2AR/M3-receptor agonist-1 has the potential for the research of respiratory tract disorders[1].
Product Specifications
CAS Number
1206887-00-4
UNSPSC
12352005
Target
Adrenergic Receptor; mAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/β2ar-m3-receptor-agonist-1.html
Solubility
10 mM in DMSO
Smiles
O=CO.O=C1NC2=C(OC1)C(C(CNCCC3=CC=C(C=C3)OCCCNCC4=CC(C(C5=CC=CC=C5)(C6=CC=CC=C6)O)=NO4)O)=CC=C2O.[x]
Molecular Formula
C38H40N4O7.xCH2O2
References & Citations
[1]Jonathan Mark Sutton, et al. Nitrogen containing heterocyclic compounds useful as bifunctional modulators of m3 receptors and beta-2 receptors. WO2010015792A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
β adrenergic receptor
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