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Mrgx2 antagonist-2

Mrgx2 antagonist-2 is a Mrgx2 antagonist (Example 123 in reference patent) with a pIC50 of 8.6. Mrgx2 antagonist-2 can be used in the research of MrgX2 -mediated diseases or disorders[1].

Product Specifications

CAS Number

[2767111-67-9]

UNSPSC

12352005

Target

Mas-related G-protein-coupled Receptor (MRGPR)

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mrgx2-antagonist-2.html

Solubility

10 mM in DMSO

Smiles

FC1([C@@H](C2=CC=[N+]([O-])C=C2)CN(CC1)[C@@H](C)C(NC3=NC=C(OC4=C(C=C(C=C4)F)F)N=C3)=O)F

Molecular Formula

C23H21F4N5O3

Molecular Weight

491.44

References & Citations

[1]Edward Brnardic, et al. Mrgx2 antagonists. Patent. WO2022073904.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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