METTL3-IN-3
METTL3-IN-3 (compound 11) is a polyheterocyclic compound, acts as METTL3 inhibitor[1].
Product Specifications
CAS Number
2767003-71-2
UNSPSC
12352005
Target
METTL3
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/mettl3-in-3.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@@H](O)[C@H](N2C=C(Br)C3=C(N)N=CN=C32)C[C@@H]1C4=CC(N5)=C(C=C5CNCC6(C7)CC7(F)C6)C=C4
Molecular Formula
C26H28BrFN6O2
Molecular Weight
555.44
References & Citations
[1]Blackaby WP, et al. Preparation of polyheterocyclic compounds as METTL3 inhibitors: World Intellectual Property Organization, WO2021111124[P]. 2021-06-10. |[2]Zeng C, et al. Roles of METTL3 in cancer: mechanisms and therapeutic targeting. J Hematol Oncol. 2020 Aug 27;13 (1) :117.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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