METTL3-IN-2
METTL3-IN-2 (compound 28) is a METTL3 inhibitor with an IC50 value of 6.1 nM. METTL3-IN-2 inhibits cell proliferation of Caov3 cancer cells[1].
Product Specifications
CAS Number
2767258-88-6
UNSPSC
12352005
Target
METTL3
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mettl3-in-2.html
Solubility
10 mM in DMSO
Smiles
COC1=CN2C(C(C3=CN(CC4=CN5C(C=CC(CNCC6(C7)CC7C6)=C5)=N4)N=N3)=C1)=CN=C2
Molecular Formula
C25H26N8O
Molecular Weight
454.53
References & Citations
[1]Hardick, DJ, et al. Preparation of heteroaromatic compounds as METTL3 inhibitory compounds. WO2022074379. 2022.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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