ATAC21
ATAC21, a linker-immune-stimulatory compound that can be formed by conjugating a noncleavable maleimide-PEG4 linker containing a succinimide group with an immune- stimulatory compound. ATAC21 can be combined with SBT-040 (anti-CD40 antibody) to form a conjugate[1].
Product Specifications
CAS Number
2101204-23-1
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atac21.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@@H](O[C@@]2([H])[C@@]1([H])OP(O)(OC[C@]3([H])[C@@]([C@H]([C@H](N4C5=C(C(N=C(N5)N)=O)N=C4)O3)O)([H])OP(O)(OC2)=O)=O)N6C7=NC=NC(NC(CCOCCOCCOCCOCCNC(CCN8C(C=CC8=O)=O)=O)=O)=C7N=C6
Molecular Formula
C38H50N12O21P2
Molecular Weight
1072.82
References & Citations
[1]Peter Armstrong Thompson, et al. Tumor targeting conjugates and methods of use thereof. WO2018140831A2.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Frequently Asked Questions
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