PAF (C18)

C18-PAF, octadecane PAF, is the ligand of platelet-activating factor and PAF G protein-coupled receptor (PAFR) . C18-PAF has renovasodilator properties and antihypertensive lipid properties. C18-PAF increases renal blood flow and causes dose-dependent systemic hypotension[1].

Product Specifications

CAS Number

[74389-69-8]

UNSPSC

12352200

Target

Platelet-activating Factor Receptor (PAFR)

Type

Biochemical Assay Reagents

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/paf-c18.html

Purity

99.00

Solubility

10 mM in DMSO

Smiles

CCCCCCCCCCCCCCCCCCOC[C@@H](OC(C)=O)COP(OCC[N+](C)(C)C)([O-])=O

Molecular Formula

C28H58NO7P

Molecular Weight

551.74

References & Citations

[1]Vargaftig BB, et al. Background and present status of research on platelet-activating factor (PAF-acether) . Ann N Y Acad Sci. 1981;370:119-37.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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