Cholesterol 5α,6α-epoxide

<strong>Cholesterol 5α,6α-epoxide</strong>_x000D_ <strong>Catalog number:</strong> B2013606_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 402.6 g/mol_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> RT_x000D_ <strong>Keywords:</strong> 5α,6α-Epoxycholestan-3β-ol_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Müller F, Arand M, Frank H, Seidel A, Hinz W, Winkler L, Henle K, Bale E, Beetham JK, Hammock BD, Oesch F. Visualization of a covalent intermediate between microsomal epoxide hydrolase, but not cholesterol epoxide hydrolase, and their substrates Eur J Biochem. 1997 Apr 15;245(2):490-6._x000D_ 2: Liao PL, Cheng YW, Li CH, Wang YT, Kang JJ. 7-Ketocholesterol and cholesterol-5alpha,6alpha-epoxide induce smooth muscle cell migration and proliferation through the epidermal growth factor receptor/phosphoinositide 3-kinase/Akt signaling pathways Toxicol Lett. 2010 Aug 16;197(2):88-96._x000D_ 3: Kloudova-Spalenkova A, Ueng YF, Wei S, Kopeckova K, Peter Guengerich F, Soucek P. Plasma oxysterol levels in luminal subtype breast cancer patients are associated with clinical data J Steroid Biochem Mol Biol. 2020 Mar;197:105566._x000D_ 4: Chan JT, Black HS. Distribution of cholesterol-5alpha,6alpha-epoxide formation and its metabolism in mouse skin J Invest Dermatol. 1976 Feb;66(02):112-6._x000D_ 5: Lemaire-Ewing S, Prunet C, Montange T, Vejux A, Berthier A, Bessada G, Corcos L, Gambert P, Anel D, Lizard G. Comparison of the cytotoxic, pro-oxidant and pro-inflammatory characteristics of different oxysterols Cell Biol Toxicol. 2005 Mar;21(2):97-114._x000D_ 6: Ghith A, Bruning JB, Bell SG. The oxidation of cholesterol derivatives by the CYP124 and CYP142 enzymes from Mycobacterium marinum J Steroid Biochem Mol Biol. 2023 May 2;231:106317._x000D_ 7: Ferderbar S, Pereira EC, Apolinario E, Bertolami MC, Faludi A, Monte O, Calliari LE, Sales JE, Gagliardi AR, Xavier HT, Abdalla DS. Cholesterol oxides as biomarkers of oxidative stress in type 1 and type 2 diabetes mellitus Diabetes Metab Res Rev. 2007 Jan;23(1):35-42._x000D_ 8: Rakove¡ L. Cholesterol load of microglia: contribution of membrane architecture changes to neurotoxic power? Arch Biochem Biophys. 2013 Sep 1;537(1):91-103._x000D_ 9: Kamgang Nzekoue F, Henle T, Caprioli G, Sagratini G, Hellwig M. Food Protein Sterylation: Chemical Reactions between Reactive Amino Acids and Sterol Oxidation Products under Food Processing Conditions Foods. 2020 Dec 17;9(12):1882._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/27414510">10: Mori TA, Croft KD, Puddey IB, Beilin LJ. Analysis of native and oxidized low-density lipoprotein oxysterols using gas chromatography-mass spectrometry with selective ion monitoring Redox Rep. 1996 Feb;2(1):25-34. </a>_x000D_ _x000D_ <strong>Products Related to Cholesterol 5α,6α-epoxide can be found at</strong> <a href="https://moleculardepot.com/product-category/Lipids/"> Lipids</a>