UHMCP1
UHMCP1 is a chemical probe of U2AF homology motifs (UHM) with a Kd of 79 μM. UHMCP1 prevents the SF3b155/U2AF65 interaction, impacts RNA splicing and cell viability. UHMCP1 has potential anticancer properties[1].
Product Specifications
CAS Number
[2103079-87-2]
UNSPSC
12352005
Target
Fluorescent Dye
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/uhmcp1.html
Purity
99.6800
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(N(C[C@]1([H])CC2)C[C@]2([H])[C@H]1N)CCC3=CNC4=CC=CC=C34
Molecular Formula
C19H27N3
Molecular Weight
297.44
References & Citations
[1]Kobayashi A, et al. Identification of a small molecule splicing inhibitor targeting UHM domains. FEBS J. 2022 Feb;289 (3) :682-698.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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