Mal-PEG8-Phe-Lys-PAB-Exatecan
Mal-PEG8-Phe-Lys-PAB-Exatecan (compound 15) is a agent-linker conjugate for ADC, composed of degradable linker Mal-PEG8-Phe-Lys-PAB and toxin molecule Exatecan (HY-13631) composition[1].
Product Specifications
CAS Number
[2679821-44-2]
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC; Topoisomerase
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-peg8-phe-lys-pab-exatecan.html
Solubility
DMSO : 180 mg/mL (ultrasonic)
Smiles
O=C(C=CC1=O)N1CCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CCCCN)C(NC(C=C3)=CC=C3COC(N[C@@H]4C5=C6C(C(N7C6)=CC([C@](O)(C(OC8)=O)CC)=C8C7=O)=NC9=CC(F)=C(C)C(CC4)=C95)=O)=O)=O)=O)=O
Molecular Formula
C73H92FN9O20
Molecular Weight
1434.56
References & Citations
[1]Manel KRAIEM. Treatment of cancer. Patent WO2021151984A1.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Camptothecins
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