Abiraterone N-oxide
Abiraterone N-oxide is a metabolite of Abiraterone (HY-148377) . Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity[1].
Product Specifications
CAS Number
[2378463-76-2]
UNSPSC
12352005
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/abiraterone-n-oxide.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@](CC=C2C3=C[N+]([O-])=CC=C3)([H])[C@@]4([H])[C@]([C@@]5(C(C[C@H](CC5)O)=CC4)C)([H])CC1
Molecular Formula
C24H31NO2
Molecular Weight
365.51
References & Citations
[1]Hu Y, Huang J, et al. Simultaneous determination of abiraterone and its five metabolites in human plasma by LC-MS/MS: Application to pharmacokinetic study in healthy Chinese subjects. J Pharm Biomed Anal. 2022 Aug 5;217:114826.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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