Budiodarone

Budiodarone (ATI-2042) is an analogue of Amiodarone with a half-life of 7 h. Budiodarone inhibits sodium, potassium, and calcium ion channels. Budiodarone is an antiarrhythmic agent and can be used for the research of atrial fibrillation[1].

Product Specifications

CAS Number

335148-45-3

Product Name Alternative

ATI-2042

UNSPSC

12352005

Target

Calcium Channel; Potassium Channel; Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/budiodarone.html

Solubility

10 mM in DMSO

Smiles

O=C(O[C@H](CC)C)CC1=C(C(C2=CC(I)=C(OCCN(CC)CC)C(I)=C2)=O)C3=CC=CC=C3O1

Molecular Formula

C27H31I2NO5

Molecular Weight

703.35

References & Citations

[1]Arya A, et al. A preliminary assessment of the effects of ATI-2042 in subjects with paroxysmal atrial fibrillation using implanted pacemaker methodology. Europace. 2009 Apr;11 (4) :458-64.