Glu (OtBu) -Val-Cit-PAB-OH
Glu (OtBu) -Val-Cit-PAB-OH (compound L5-1c) is an non-cleavable ADC linker. Glu (OtBu) -Val-Cit-PAB-OH has been used to synthesis protein-tubulysin conjugates[1].
Product Specifications
CAS Number
[2757059-05-3]
UNSPSC
12352203
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/glu-otbu-val-cit-pab-oh.html
Solubility
10 mM in DMSO
Smiles
OCC(C=C1)=CC=C1NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@@H](N)CCC(OC(C)(C)C)=O)=O)=O)=O
Molecular Formula
C27H44N6O7
Molecular Weight
564.67
References & Citations
[1]Amy Han. Tubulysins and protein-tubulysin conjugates. WO2021262910A2
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
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