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Glu (OtBu) -Val-Cit-PAB-OH

Glu (OtBu) -Val-Cit-PAB-OH (compound L5-1c) is an non-cleavable ADC linker. Glu (OtBu) -Val-Cit-PAB-OH has been used to synthesis protein-tubulysin conjugates[1].

Product Specifications

CAS Number

[2757059-05-3]

UNSPSC

12352203

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/glu-otbu-val-cit-pab-oh.html

Solubility

10 mM in DMSO

Smiles

OCC(C=C1)=CC=C1NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@@H](N)CCC(OC(C)(C)C)=O)=O)=O)=O

Molecular Formula

C27H44N6O7

Molecular Weight

564.67

References & Citations

[1]Amy Han. Tubulysins and protein-tubulysin conjugates. WO2021262910A2

Shipping Conditions

Room temperature

Scientific Category

ADC Related

Clinical Information

No Development Reported

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