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PKM2 activator 4

PKM2 activator 4 is a PKM2 activator with an AC50 value of 1-10 μM. PKM2 activator 4 can be used for the research of cancer[1].

Product Specifications

CAS Number

[781656-66-4]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

Pyruvate Kinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pkm2-activator-4.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=CC=C2N(C)C(OC2=C1)=O)(N(C)CC3=CC=CC=C3)=O

Molecular Formula

C16H16N2O4S

Molecular Weight

332.37

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Salituro Francesco G, et al. Pyruvate kinase M2 modulators for use in the treatment of cancer. WO2010129596. 2010.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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