PD-1/PD-L1-IN-28
PD-1/PD-L1-IN-28 (compound 3) is an immune checkpoint inhibitor of PD-1/PD-L1 signaling pathway (IC50=0.744 µM) . PD-1/PD-L1-IN-28 shows good research potential in tumor immunity[1].
Product Specifications
CAS Number
[2499965-07-8]
UNSPSC
12352005
Target
PD-1/PD-L1
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pd-1-pd-l1-in-28.html
Solubility
10 mM in DMSO
Smiles
OCCNCC1=CC=C(NC2=NN=C(C3=C(C)C(C4=CC=CC=C4)=CC=C3)O2)C=C1
Molecular Formula
C24H24N4O2
Molecular Weight
400.47
References & Citations
[1]Jiang Sheng, et al. Preparation of phenyl substituted five membered heterocyclic compounds as immunocheckpoint inhibitors of PD-1 / PD-L1 signaling pathway. Patent WO2021031788A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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