PD-1/PD-L1-IN-28
PD-1/PD-L1-IN-28 (compound 3) is an immune checkpoint inhibitor of PD-1/PD-L1 signaling pathway (IC50=0.744 µM) . PD-1/PD-L1-IN-28 shows good research potential in tumor immunity[1].
Product Specifications
CAS Number
[2499965-07-8]
UNSPSC
12352005
Target
PD-1/PD-L1
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pd-1-pd-l1-in-28.html
Solubility
10 mM in DMSO
Smiles
OCCNCC1=CC=C(NC2=NN=C(C3=C(C)C(C4=CC=CC=C4)=CC=C3)O2)C=C1
Molecular Formula
C24H24N4O2
Molecular Weight
400.47
References & Citations
[1]Jiang Sheng, et al. Preparation of phenyl substituted five membered heterocyclic compounds as immunocheckpoint inhibitors of PD-1 / PD-L1 signaling pathway. Patent WO2021031788A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
039293-HRP 200 µL
OPTN, ID (OPTN, FIP2, GLC1E, HIP7, HYPL, NRP, Optineurin, E3-14.7K-interacting protein, FIP-2, Huntingtin yeast partner L, Huntingtin-interacting protein 7, Huntingtin-interacting protein L, NEMO-related protein, Optic neuropathy-inducing protein, Transcription factor IIIA-interacting protein) (Azide free) (HRP) discontinued
Ask
View Details 
![Human Monoclonal Siglec-15 Antibody (NC318) [Janelia Fluor 585]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
NBP3-28170JF585 0.1 mL
Human Monoclonal Siglec-15 Antibody (NC318) [Janelia Fluor 585]
Ask
View Details