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L-Afegostat

L-Afegostat (5-epi-Isofagomine) is a glycosidase inhibitor. L-Afegostat is an iminosugar that can be used for the synthesis of carbohydrates. L-Afegostat shows enzyme inhibition to β-Glucosidase with an Ki of 30 μM[1].

Product Specifications

CAS Number

202979-51-9

Product Name Alternative

5-epi-Isofagomine

UNSPSC

12352005

Target

Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/l-afegostat.html

Solubility

10 mM in DMSO

Smiles

O[C@@H]1CNC[C@@H](CO)[C@H]1O

Molecular Formula

C6H13NO3

Molecular Weight

147.17

References & Citations

[1]Pandey G, et al. A new access to polyhydroxy piperidines of the azasugar class: synthesis and glycosidase inhibition studies. Org Biomol Chem. 2003 Oct 7;1 (19) :3321-6.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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