KRAS G12C inhibitor 56
KRAS G12C inhibitor 56 (compound IC-6) is a potent SOS1 inhibitor with an IC50 of 1.6 nM. KRAS G12C inhibitor 56 can be used in cancer research[1].
Product Specifications
CAS Number
2749963-77-5
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12c-inhibitor-56.html
Solubility
10 mM in DMSO
Smiles
C=CC(N1CCC(CC1)OC2=NC(C3=CC([C@@]4(C)CCCC5=C4C(C#N)=C(S5)N)=NO3)=NC(O[C@H]([C@@H]6CCCN6C)C)=C2)=O
Molecular Formula
C32H39N7O4S
Molecular Weight
617.76
References & Citations
[1]Jason ABBOTT, et al. Annulated 2-amino-3-cyano thiophenes and derivatives for the treatment of cancer. Patent WO2021245051A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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