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SF-1 antagonist-1

SF-1 antagonist-1 (compound 11) is a antagonist of steroidogenic factor 1 (SF-1) . SF-1 antagonist-1 affects SF-1 transcriptional activity with an EC50 value of [1].

Product Specifications

CAS Number

[2842079-86-9]

UNSPSC

12352005

Target

Orphan Nuclear Receptor; Orphan Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sf-1-antagonist-1.html

Solubility

10 mM in DMSO

Smiles

FC(F)(F)C(C=C1)=CC=C1NC2=NN(C)C3=C2N=CN(CC(NC4=CC=C(OC)C(F)=C4)=O)C3=O

Molecular Formula

C22H18F4N6O3

Molecular Weight

490.41

References & Citations

[1]Raheja Neil, et al. PYRAZOLOPYRIMIDINONE COMPOUNDS. WO2022204481. 2022.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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