SF-1 antagonist-1
SF-1 antagonist-1 (compound 11) is a antagonist of steroidogenic factor 1 (SF-1) . SF-1 antagonist-1 affects SF-1 transcriptional activity with an EC50 value of [1].
Product Specifications
CAS Number
[2842079-86-9]
UNSPSC
12352005
Target
Orphan Nuclear Receptor; Orphan Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sf-1-antagonist-1.html
Solubility
10 mM in DMSO
Smiles
FC(F)(F)C(C=C1)=CC=C1NC2=NN(C)C3=C2N=CN(CC(NC4=CC=C(OC)C(F)=C4)=O)C3=O
Molecular Formula
C22H18F4N6O3
Molecular Weight
490.41
References & Citations
[1]Raheja Neil, et al. PYRAZOLOPYRIMIDINONE COMPOUNDS. WO2022204481. 2022.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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