MU1700
MU1700, a chemical probe, is an orally active and potent ALK1/2 inhibitor with IC50s of 13 nM and 6 nM, respectively. MU1700 shows cell membrane permeability and high brain permeability[1].
Product Specifications
UNSPSC
12352005
Target
TGF-β Receptor
Type
Reference compound
Related Pathways
TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mu1700.html
Solubility
10 mM in DMSO
Smiles
N1(C2=CC=C(C3=CC(OC=C4C5=C(C=CC=C6)C6=NC=C5)=C4N=C3)C=C2)CCNCC1
Molecular Formula
C26H22N4O
Molecular Weight
406.48
References & Citations
[1]MU1700 Chemical probe for ALK1 and ALK2 protein kinases
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ALK1; ALK2; ALK6
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