BAY-3153
BAY-3153, a chemical probe, is a selective CCR1 (C-C motif chemokine receptor 1) antagonist (human IC50=3 nM; rat IC50=11 nM; mice IC50=81 nM) [1].
Product Specifications
CAS Number
[2771319-69-6]
UNSPSC
12352005
Target
CCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/bay-3153.html
Solubility
10 mM in DMSO
Smiles
O[C@H](C1)C[C@H](C(N2C[C@H]3N(C4=CC=C(Cl)C(OCC)=C4)[C@H](COC3)C2)=O)N1C5=CC=C(Cl)C=C5
Molecular Formula
C25H29Cl2N3O4
Molecular Weight
506.42
References & Citations
[1]https://www.sgc-ffm.uni-frankfurt.de/#!specificprobeoverview/BAY-3153
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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