TFEB Decoy ODN (sodium)
TFEB Decoy ODN sodium is a synthetic oligonucleotide with a hairpin ring structure, which were designed to inhibit Transcription factor EB (TFEB) . TFEB decoy ODN inhibited fibrosis and autophagy in a UUO mouse model. The TFEB decoy ODNs also showed anti-inflammatory effects.
Product Specifications
UNSPSC
12352208
Target
Autophagy; HIF/HIF Prolyl-Hydroxylase; Interleukin Related
Type
Oligonucleotides
Related Pathways
Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/tfeb-decoy-odn.html
Purity
90.24
Solubility
10 mM in DMSO
Smiles
[TFEBDecoyODN(sodium)]
References & Citations
[1]Lee SJ, Kim YA, Park KK. Anti-Fibrotic Effect of Synthetic Noncoding Decoy ODNs for TFEB in an Animal Model of Chronic Kidney Disease. Int J Mol Sci. 2022;23 (15) :8138.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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