Tolindate
Product Specifications
UNSPSC Description
Tolindate is a potent PXR agonist with an EC50 value of 8.3 μM. Tolindate shows antifungal activity[1][2].
Target Antigen
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/tolindate.html
Solubility
10 mM in DMSO
Smiles
S=C(N(C)C1=CC=CC(C)=C1)OC2=CC=C3C(CCC3)=C2
Molecular Weight
297.41
References & Citations
[1]Lynch C, et al. Characterization of human pregnane X receptor activators identified from a screening of the Tox21 compound library. Biochem Pharmacol. 2021 Feb;184:114368.|[2]Pastor L, et al. New antifungals selected by molecular topology. Bioorg Med Chem Lett. 1998 Sep 22;8(18):2577-82.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148223/Tolindate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148223/
Clinical Information
No Development Reported
CAS Number
27877-51-6
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1084305 Inquire
Recombinant Lactococcus lactis subsp.cremoris Group II intron-encoded protein ltrA (ltrA), partial
Ask
View Details 