HBPC–GSH
HBPC-GSH is a glyoxalase (Glo) inhibitor (cGloI IC50=0.6 μM; cGloII IC50=1.6 μM), a glutathione derivative. HBPC-GSH can be used in antimalarial research[1].
Product Specifications
CAS Number
156727-62-7
UNSPSC
12352005
Target
Glyoxalase (GLO) ; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hbpc-gsh.html
Solubility
10 mM in DMSO
Smiles
OC([C@@H](N)CCC(N[C@H](C(NCC(O)=O)=O)CSC(N(C1=CC=C(C=C1)Br)O)=O)=O)=O
Molecular Formula
C17H21BrN4O8S
Molecular Weight
521.34
References & Citations
[1]Akoachere M, et al. Characterization of the glyoxalases of the malarial parasite Plasmodium falciparum and comparison with their human counterparts. Biol Chem. 2005 Jan;386 (1) :41-52.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Plasmodium
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