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CDK2/4/6-IN-2

CDK2/4/6-IN-2 is a CKD2/4/6 inhibitor, with IC50 values less than 1 μM, 10 nM, 100 nM respectively[1].

Product Specifications

CAS Number

2531748-80-6

UNSPSC

12352005

Target

CDK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cdk2-4-6-in-2.html

Purity

98.20

Solubility

DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC(N1CCN(C2=CN=C(NC3=NC=CC(C4=CC5=C(N=CN5C(C)C)C(F)=N4)=N3)C=C2)CC1)C

Molecular Formula

C25H30FN9

Molecular Weight

475.56

References & Citations

[1]Hu Zhilong, et al. Preparation of pyrimidine derivatives and related heterocycles as CDK inhibitors for the treatment of cancer. Patent. WO2020224568 A1

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CDK2; CDK4; CDK6

Available Sizes

Frequently Asked Questions

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