CDK2/4/6-IN-2
CDK2/4/6-IN-2 is a CKD2/4/6 inhibitor, with IC50 values less than 1 μM, 10 nM, 100 nM respectively[1].
Product Specifications
CAS Number
[2531748-80-6]
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk2-4-6-in-2.html
Purity
98.20
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC(N1CCN(C2=CN=C(NC3=NC=CC(C4=CC5=C(N=CN5C(C)C)C(F)=N4)=N3)C=C2)CC1)C
Molecular Formula
C25H30FN9
Molecular Weight
475.56
References & Citations
[1]Hu Zhilong, et al. Preparation of pyrimidine derivatives and related heterocycles as CDK inhibitors for the treatment of cancer. Patent. WO2020224568 A1
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK2; CDK4; CDK6
Available Sizes
Curated Selection
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