Trypanothione

Trypanothione is a bis-glutathionyl derivative, found in trypanosomatids. Trypanothione shows the protection against oxidative stress[1][2][3].

Product Specifications

CAS Number

96304-42-6

UNSPSC

12352005

Target

Drug Derivative

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/trypanothione.html

Solubility

10 mM in DMSO

Smiles

OC([C@@H](N)CCC(N[C@@H]1C(NCC(NCCCCNCCCNC(CNC([C@H](CSSC1)NC(CC[C@H](N)C(O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C27H47N9O10S2

Molecular Weight

721.85

References & Citations

[1]Manta B, et al. Trypanothione: a unique bis-glutathionyl derivative in trypanosomatids. Biochim Biophys Acta. 2013 May;1830 (5) :3199-216.|[2]Fairlamb AH, et al. Metabolism and functions of trypanothione in the Kinetoplastida. Annu Rev Microbiol. 1992;46:695-729.|[3]Krauth-Siegel RL, et al. The parasite-specific trypanothione metabolism of trypanosoma and leishmania. Biol Chem. 2003 Apr;384 (4) :539-49.