Mcl-1 inhibitor 9
Mcl-1 inhibitor 9 (example 2) is a myeloid cell leukemia 1 (Mcl-1) inhibitor with IC50 value of 0.21889 nM. Mcl-1 inhibitor 9 shows anti-tumor activity[1].
Product Specifications
CAS Number
[1883727-31-8]
UNSPSC
12352005
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mcl-1-inhibitor-9.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C([C@@]2(CCC3)CN4C5=CC(C(NS(=O)([C@@H]([C@H](C/C=C\[C@@H]([C@@]6([H])[C@](CC6)([H])C4)O)C)C)=O)=O)=CC=C5OC2)C3=C1
Molecular Formula
C32H39ClN2O5S
Molecular Weight
599.18
References & Citations
[1]Sean P. Brown, et al. Tetrahydronaphthalene derivatives that inhibit mcl-1 protein. WO2016033486A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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