Mcl-1 inhibitor 9

Mcl-1 inhibitor 9 (example 2) is a myeloid cell leukemia 1 (Mcl-1) inhibitor with IC50 value of 0.21889 nM. Mcl-1 inhibitor 9 shows anti-tumor activity[1].

Product Specifications

CAS Number

[1883727-31-8]

UNSPSC

12352005

Target

Bcl-2 Family

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mcl-1-inhibitor-9.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC=C([C@@]2(CCC3)CN4C5=CC(C(NS(=O)([C@@H]([C@H](C/C=C\[C@@H]([C@@]6([H])[C@](CC6)([H])C4)O)C)C)=O)=O)=CC=C5OC2)C3=C1

Molecular Formula

C32H39ClN2O5S

Molecular Weight

599.18

References & Citations

[1]Sean P. Brown, et al. Tetrahydronaphthalene derivatives that inhibit mcl-1 protein. WO2016033486A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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