S1P5 receptor agonist-1
S1P5 receptor agonist-1 (example 6) is a potent and selective agonist of S1P5 receptor with an EC50 value of 20 nM[1].
Product Specifications
CAS Number
[2373330-78-8]
UNSPSC
12352005
Target
LPL Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/s1p5-receptor-agonist-1.html
Solubility
10 mM in DMSO
Smiles
FC(F)(F)CCCOC1=CC=C(C=C([C@H](C2)C)CN3CC(C3)C(O)=O)C2=C1
Molecular Formula
C20H24F3NO3
Molecular Weight
383.40
References & Citations
[1]Otani Shuhei, et al. Salt and crystal form of compound having agonistic activity to S1P5 receptor: World Intellectual Property Organization, WO2021033729A[P]. 2021-02-25.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
S1PR5
Curated Selection
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Solute Carrier Family 7, SCL7A5 (Cationic Amino Acid Transporter, Y+ System), Member 5 (Solute Carrier Family 7 Member 5, SLC7A5, 4F2 Light Chain, 4F2 LC, 4F2LC, CD98 Light Chain, CD98LC, DC49, hLAT1, Integral Membrane Protein E16, L-type Amino Acid Transporter 1, Large Neutral Amino Acids Transporter, MPE16, Sodium-independent Neutral Amino Acid Transporter, Y+ System Cationic Amino Acid Transporter)
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