L-Fd4A
Product Specifications
UNSPSC Description
L-Fd4A is an adenine derivative. L-Fd4A has anti-human immunodeficiency virus (HIV) (EC50=1.5 μM) and anti-hepatitis B virus (HBV) (EC50=1.7 μM) activity. L-Fd4A has low cytotoxicity[1].
Target Antigen
HBV; HIV; Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Anti-infection;Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/l-fd4a.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1O[C@H](N2C3=NC=NC(N)=C3N=C2)C(F)=C1
Molecular Weight
251.22
References & Citations
[1]Lee K, et, al. Synthesis and anti-HIV and anti-HBV activities of 2'-fluoro-2', 3'-unsaturated L-nucleosides. J Med Chem. 1999 Apr 8;42(7):1320-8.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148172/L-Fd4A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148172/
Clinical Information
No Development Reported
CAS Number
210474-65-0
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