L-Fd4A

L-Fd4A is an adenine derivative. L-Fd4A has anti-human immunodeficiency virus (HIV) (EC50=1.5 μM) and anti-hepatitis B virus (HBV) (EC50=1.7 μM) activity. L-Fd4A has low cytotoxicity[1].

Product Specifications

CAS Number

[210474-65-0]

UNSPSC

12352005

Target

HBV; HIV; Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/l-fd4a.html

Solubility

10 mM in DMSO

Smiles

OC[C@@H]1O[C@H](N2C3=NC=NC(N)=C3N=C2)C(F)=C1

Molecular Formula

C10H10FN5O2

Molecular Weight

251.22

References & Citations

[1]Lee K, et, al. Synthesis and anti-HIV and anti-HBV activities of 2'-fluoro-2', 3'-unsaturated L-nucleosides. J Med Chem. 1999 Apr 8;42 (7) :1320-8.