Delafloxacin-d5

Delafloxacin-d5 is deuterium labeled Delafloxacin. Delafloxacin (RX-3341; WQ-3034; ABT492) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumonia[1].

Product Specifications

Product Name Alternative

RX-3341-d5; WQ-3034-d5; ABT492-d5

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Bacterial; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Others

Applications

COVID-19-immunoregulation

Field of Research

Infection

Purity

99.76

Solubility

10 mM in DMSO

Smiles

O=C(C1=CN(C2=C(C(N3C([2H])([2H])C(C3([2H])[2H])([2H])O)=C(C=C2C1=O)F)Cl)C4=NC(N)=C(C=C4F)F)O

Molecular Formula

C18H7D5ClF3N4O4

Molecular Weight

445.79

Precautions

H302, H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Lepak AJ, et al. In Vivo Pharmacodynamic Target Assessment of Delafloxacin against Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumoniae in a Murine Lung Infection Model. Antimicrob Agents Chemother. 2016 Jul 22;60 (8) :4764-9.